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Neurology

Vyvgart (efgartigimod alfa)

FcRn antagonist for myasthenia gravis.

Duration: About 1 hour
Schedule: 4 weekly infusions per cycle, cycles every 8–12 weeks
Schedule Vyvgart For providers
Conditions

What Vyvgart treats.

  • Generalized myasthenia gravis (anti-AChR antibody positive)
  • Chronic inflammatory demyelinating polyneuropathy (CIDP, with Vyvgart Hytrulo)
How it works

The mechanism.

Vyvgart (efgartigimod) blocks the neonatal Fc receptor (FcRn), accelerating the breakdown of pathogenic IgG antibodies that drive myasthenia gravis. By specifically targeting harmful antibodies without broadly suppressing immunity, Vyvgart offers a more selective approach than older immunosuppressants.

What to expect

Your Vyvgart infusion experience.

Vyvgart is given in cycles of 4 weekly infusions, with cycles repeated based on clinical response (typically every 8 to 12 weeks). Each infusion lasts 1 hour. Most patients notice meaningful improvement in muscle strength within the first cycle.

Insurance & cost

Insurance & out-of-pocket cost.

Vyvgart is covered by most commercial insurance and Medicare Part B when prescribed by your physician for an FDA-approved indication. We verify your benefits before your first infusion and handle prior authorization on your behalf. Most commercially insured patients pay only their standard specialty copay — typically $20–$100 per visit. Manufacturer copay assistance programs may further reduce your cost.

This page is for educational purposes only. Information about Vyvgart (efgartigimod alfa) is provided for general patient information and does not replace medical advice. Vyvgart requires a physician’s prescription and is administered based on your physician’s orders, your diagnosis, and your individual clinical picture. Talk with your prescribing physician about whether Vyvgart is right for you, what side effects to watch for, and how it fits into your overall treatment plan.

Ready to start

Begin your Vyvgart infusion at Arbor.

Ask your physician to refer you, or contact us directly. We coordinate with your provider and handle the insurance work on your behalf.