What Tysabri treats.
- Relapsing forms of multiple sclerosis
- Moderate to severe Crohn’s disease
The mechanism.
Tysabri (natalizumab) prevents immune cells from crossing into the brain or gut tissues by blocking the alpha-4 integrin protein on their surface. This stops the inflammatory attack at the source — one of the most effective mechanisms available for both MS and Crohn’s.
Your Tysabri infusion experience.
Tysabri infusions take about 1 hour and are given every 4 weeks. Patients are required to enroll in the TOUCH program, which monitors for the rare but serious complication PML (progressive multifocal leukoencephalopathy). Regular MRI and JC virus antibody monitoring are part of the protocol.
Insurance & out-of-pocket cost.
Tysabri is covered by most commercial insurance and Medicare Part B when prescribed by your physician for an FDA-approved indication. We verify your benefits before your first infusion and handle prior authorization on your behalf. Most commercially insured patients pay only their standard specialty copay — typically $20–$100 per visit. Manufacturer copay assistance programs may further reduce your cost.