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Infectious Disease

Rezzayo (rezafungin)

Once-weekly IV antifungal for invasive candidiasis.

Duration: About 1 hour
Schedule: Loading dose, then once weekly
Schedule Rezzayo For providers
Conditions

What Rezzayo treats.

  • Candidemia (Candida bloodstream infection)
  • Invasive candidiasis
  • Patients transitioning from inpatient daily echinocandin therapy to outpatient maintenance
How it works

The mechanism.

Rezzayo (rezafungin) is an echinocandin antifungal that inhibits fungal cell wall synthesis, killing Candida species and other invasive fungi. Unlike traditional echinocandins that require daily infusions, Rezzayo’s extended half-life allows once-weekly dosing — making outpatient treatment feasible for patients who would otherwise need extended hospitalization or daily clinic visits.

What to expect

Your Rezzayo infusion experience.

Rezzayo is administered as a 1-hour IV infusion. After an initial loading dose, maintenance is once weekly for the duration of treatment, typically 14 days from the first negative blood culture. We coordinate with your prescribing infectious disease specialist on dosing and treatment duration.

Insurance & cost

Insurance & out-of-pocket cost.

Rezzayo is covered by most commercial insurance and Medicare Part B when prescribed by your physician for an FDA-approved indication. We verify your benefits before your first infusion and handle prior authorization on your behalf. Most commercially insured patients pay only their standard specialty copay — typically $20–$100 per visit. Manufacturer copay assistance programs may further reduce your cost.

This page is for educational purposes only. Information about Rezzayo (rezafungin) is provided for general patient information and does not replace medical advice. Rezzayo requires a physician’s prescription and is administered based on your physician’s orders, your diagnosis, and your individual clinical picture. Talk with your prescribing physician about whether Rezzayo is right for you, what side effects to watch for, and how it fits into your overall treatment plan.

Ready to start

Begin your Rezzayo infusion at Arbor.

Ask your physician to refer you, or contact us directly. We coordinate with your provider and handle the insurance work on your behalf.