What Benlysta treats.
- Systemic lupus erythematosus (SLE)
- Lupus nephritis
The mechanism.
Benlysta (belimumab) blocks B-lymphocyte stimulator (BLyS), a protein that helps autoreactive B cells survive. By reducing BLyS activity, Benlysta lowers the number of B cells producing autoantibodies that drive lupus inflammation.
Your Benlysta infusion experience.
Benlysta infusions take about 1 hour. After three loading doses (weeks 0, 2, and 4), maintenance is every 4 weeks. Patients often see meaningful improvement in fatigue, joint pain, and skin symptoms over the first 6 months.
Insurance & out-of-pocket cost.
Benlysta is covered by most commercial insurance and Medicare Part B when prescribed by your physician for an FDA-approved indication. We verify your benefits before your first infusion and handle prior authorization on your behalf. Most commercially insured patients pay only their standard specialty copay — typically $20–$100 per visit. Manufacturer copay assistance programs may further reduce your cost.